Co-phenotrope is an anti-diarrheal drug sometimes used in the treatment of your Irritable Bowel Syndrome.
This drug is generally used for short term use if your diarrhea is bad, but sometimes has the unwanted side effect of constipation if taken regularly.
When you are looking to purchase this medication, you may find it under the trade names of Lomotil, Diarphen and Tropergen.
The active ingredients are Atropine Sulfate and Diphenoxylate Hydrochloride
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It is used in Irritable Bowel Syndrome (Unlicensed use in UK) and as an aid to rehydration in acute diarrhea and in chronic mild Ulcerative colitis too.
If symptoms don't settle always seek advice from your doctor.
When considering this drug it is important to discuss with a health care professional to see if it is right for you.
In particular, you should always seek medical advice if:
This particular medication has many potential side effects including
May cause drowsiness - avoid driving or operating machinery in this situation.
Initially 4 tablets, followed by 2 tablets every 6 hours until your diarrhea has come under control.
This medication comes in a variety of different formulations which makes for easy use.
It is available as tablets, chewable tablets, suspension, effervescent tablets, syrup and as an injection.
This drug is useful in diarrhea predominant Irritable Bowel Syndrome as it helps with both the frequency in which you are going to the toilet as well as the cramps.
It can also cause drowsiness (although seldom a problem), so for anyone with night time diarrhea, this can aid a more restful sleep as well as reducing the frequency that you have to go to the toilet.
As a short term aid in the management of your symptoms, it is very good, although I would personally recommend non-drug options in the longer term rather than the use of this drug alone.
1) A comparison of lomotil and imodium in acute non-specific diarrhoea.Jaffé G.J Int Med Res. 1977;5(3):195-8.
2) Acute effect of diphenoxylate with atropine (Lomotil) in patients with chronic diarrhea and fecal incontinence.Harford WV, Krejs GJ, Santa Ana CA, Fordtran JS.Gastroenterology. 1980 Mar;78(3):440-3.
3) Diphenoxylate hydrochloride (Lomotil) in the treatment of acute diarrhoea.Lustman F, Walters EG, Shroff NE, Akbar FA.Br J Clin Pract. 1987 Mar;41(3):648-51
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